凝集素樣氧化低密度脂蛋白受體1(LOX1)單克隆抗體
Monoclonal Antibody to Lectin Like Oxidized Low Density Lipoprotein Receptor 1 (LOX1)
OLR1; CLEC8A; SCARE1; Oxidized low-density lipoprotein receptor 1; C-type lectin domain family 8 member A; Lectin-like oxidized LDL receptor 1; Lectin-type oxidized LDL receptor 1
- 編號UMAB859Hu24
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 來源單抗制備
- 宿主小鼠
- 效價(克隆號)C4
- Ig亞型 IgG1 Kappa
- 純化方式蛋白A + 蛋白G親和純化
- 標(biāo)記物無標(biāo)記物
- 免疫原 RPB859Hu01-凝集素樣氧化低密度脂蛋白受體1(LOX1)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性狀液體
- 濃度1mg/ml
- 且適物種Rattus norvegicus (Rat，大鼠)
- 應(yīng)用WB; ICC/IF
如果抗體需用于流式細胞術(shù)，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 326 ¥ 760 ¥ 1086 ¥ 2715 ¥ 10860
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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AF488 staining on IF;
Sample: Hela cell
Primary Ab: 30μg/ml Mouse Anti-Human LOX1 Antibody
Second Ab: 2μg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu11)
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Western Blot; Sample: Lane1: Human Placenta lysate; Lane2: Rat Liver lysate; Lane3: Rat Thymus lysate Primary Ab: 0.2μg/ml Mouse Anti-Human LOX1 Antibody Second Ab: 0.2μg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
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通過ISO 9001、ISO 13485質(zhì)量體系認證
特異性
該抗體是針對LOX1的小鼠單克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別LOX1。
用法
Western blotting: 0.5-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
贈品
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| URPB859Hu01 | 凝集素樣氧化低密度脂蛋白受體1(LOX1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAB859Hu01 | 凝集素樣氧化低密度脂蛋白受體1(LOX1)多克隆抗體 | WB; IHC; ICC/IF |
| UMAB859Hu23 | 凝集素樣氧化低密度脂蛋白受體1(LOX1)單克隆抗體 | ICC/IF |
| UMAB859Hu21 | 凝集素樣氧化低密度脂蛋白受體1(LOX1)單克隆抗體 | WB; ICC/IF |
| UMAB859Hu22 | 凝集素樣氧化低密度脂蛋白受體1(LOX1)單克隆抗體 | ICC/IF |
| UMAB859Hu24 | 凝集素樣氧化低密度脂蛋白受體1(LOX1)單克隆抗體 | WB; ICC/IF |
| USEB859Hu | 凝集素樣氧化低密度脂蛋白受體1(LOX1)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| ULMB859Hu | 凝集素樣氧化低密度脂蛋白受體1(LOX1)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
| UKSB859Hu01 | 凝集素樣氧化低密度脂蛋白受體1(LOX1)檢測試劑盒DIY材料(酶聯(lián)免疫吸附試驗法) | Main materials for "Do It (ELISA Kit) Yourself". |
參考文獻
| 雜志 | 參考文獻 |
| Clinical Cardiology | Circulating Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels Are Associated With Angiographic Coronary Lesion Complexity in Patients With Coronary Artery Diseas [PubMed: 21400544] |
| Coronary Artery Disease | Postprocedural serum sLOX-1 levels are associated with coronary in-stent restenosis in patients with stable coronary artery disease [LWW: 06000] |
| Clinical Biochemistry | Soluble lectin-like oxidized low-density lipoprotein receptor-1 levels in synovial fluid are correlated with disease severity of knee osteoarthritis [ScienceDirect: S0009912011004905] |
| Mediators of Inflammation | Pregnancy Followed by Delivery May Affect Circulating Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels in Women of Reproductive Age [PubMed: 22619487] |
| Dicle Medical Journal | Lectin-like oxidized low density lipoprotein receptor 1(LOX-1) levels and endothelial dysfunction in patients with primary essential hyperhidrosis/Primer esansiyel hiperhidroz hastalarinda lektin benzeri okside düsük dansiteli lipoprotein reseptor 1(LOX-1) düzeyleri ve endotel disfonksiyonu [Readperiodicals: Source] |
| Journal of Clinical Laboratory Analysis | Soluble Lectin-Like Oxidized LDL Receptor 1 as a Possible Mediator of Endothelial Dysfunction in Patients With Metabolic Syndrome [Pubmed:24798146] |
| Journal of Human Hypertension | Endothelial damage in white coat hypertension: role of lectin-like oxidized low-density lipoprotein-1 [Pubmed:25007999] |
| Gynecologic and Obstetric Investigation | Inhibition of Lectin-Like Oxidized Low-Density Lipoprotein Receptor 1 Protects against Plasma/Hypoxia-Mediated Trophoblast Dysfunction Associated with Preeclampsia [Pubmed:25633310] |
| World J Gastroenterol | Increased serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels in patients with biopsy-proven nonalcoholic fatty liver disease [PubMed: 26185381] |
| Genetic Testing and Molecular Biomarkers | Serum sLOX-1 Levels Are Correlated with the Presence and Severity of Obstructive Sleep Apnea [PubMed: 25825846] |
| Neurotoxicology. | 27-Hydroxycholesterol regulates cholesterol synthesis and transport in C6 glioma cells. [pubmed:28167099] |
| Journal of the American?Heart?Association | Increased Levels of Lectin‐Like Oxidized Low‐Density Lipoprotein Receptor‐1 in Ischemic Stroke and Transient Ischemic Attack [Pubmed:29330254] |
| Higher serum lectin-like oxidized low-density lipoprotein receptor-1 in patients with stable coronary artery disease is associated with major adverse?… [] | |
| Disease Markers | Baseline Serum sLOX-1 Concentrations Are Associated with 2-Year Major Adverse Cardiovascular and Cerebrovascular Events in Patients after Percutaneous?… [Pubmed: 31772687] |
| Reproductive Biology | Polycystic ovary syndrome and endothelial dysfunction: A potential role for soluble lectin-like oxidized low density lipoprotein receptor-1 [Pubmed: 32409108] |
| Int J Cancer | The oxidized‐LDL/LOX‐1 axis in tumor endothelial cells enhances metastasis by recruiting neutrophils and cancer cells [Pubmed:35608341] |
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